DOPAMINE COMPUTATION
DOPAMINE (INTROPIN)
Action: Positive inotropic effect on the heart
Indications: Hypotension, Low cardiac output states
Must know:
1. FORMULA
| Doctor’s order (mcg/kg/min) | X | Client’s weight (kg) | X | 60 min/hr |
|
| ||||
| Stock dose (mcg/ml) | ||||
2. AVAILABLE DOSAGE
Single concentration: 200 mg/250 ml = 8000 mcg/ml =
Double concentration: 400 mg/250 ml = 1600 mcg/ml
Triple concentration: 600 mg/250 ml = 2400 mcg/ml
Conversion to microgram:
Conversion factor: 1000 mcg = 1 mg
| 200 mg | | 1000 mcg |
|
| X |
|
| 250 ml | | 1 mg |
|
| | 1000 mcg |
|
| X |
|
| 250 ml | |
|
| 200,000 mcg |
|
|
| 250 ml |
|
|
Sample Problem:
A client was ordered to have an infusion of dopamine via infusion pump at 15mcg/kg/min. The client weighs 176 pounds. The medication comes in 400mg in 250ml of D5W. Compute for ml/hr:
_________________ml/hr
STEP 1: Know the given.
Doctor’s order: 8mcg/kg/min
Client’s weight: 176 lb or 76.36
Available stock: 250 mg/250 ml
Convert 168 lb to kg.
Conversion factor: 1 kg = 2.2 lb
| 176 lb | | 1 kg |
|
| X |
|
| 1 | | 2.2 lb |
| 176 lb | | 1 kg |
|
| X |
|
| 1 | | 2.2 lb |
| 80 kg |
|
|
| 1 |
| 80 kg |
Step 2: Substitute the given to the formula.
| Doctor’s order (mcg/kg/min) | X | Client’s weight (kg) | X | 60 min/hr |
|
| ||||
| Stock dose (mcg/ml) | ||||
| Doctor’s order (15mcg/kg/min) | X | Client’s weight (80 kg) | X | 60 min/hr |
|
| ||||
| Stock dose (1600 mcg/ml) | ||||
| 15mcg/kg/min | X | 80 kg | X | 60 min/hr |
|
| ||||
| 1600 mcg/ml | ||||
|
| X |
| X |
|
|
| ||||
| 1600 mcg/ml | ||||
| 40 ml/hr |
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DOBUTAMINE COMPUTATION
DOBUTAMINE (DOBUTREX)
Action: Inotropic support
Indications: Left ventricular dysfunction, congestive heart failure
Must know:
3. FORMULA
| Doctor’s order (mcg/kg/min) | X | Client’s weight (kg) | X | 60 min/hr |
|
| ||||
| Stock dose (mcg/ml) | ||||
4. AVAILABLE DOSAGE
Single concentration: 250 mg/250 ml = 1000 mcg/ml
Double concentration: 500 mg/250 ml = 2000 mcg/ml = 0.03 ml/min/hr/mcg
Triple concentration: 750 mg/250 ml = 3000 mcg/ml
Conversion to microgram:
Conversion factor: 1000 mcg = 1 mg
| 250 mg | | 1000 mcg |
|
| X |
|
| 250 ml | | 1 mg |
|
| | 1000 mcg |
|
| X |
|
| 250 ml | |
|
| 250,000 mcg |
|
|
| 250 ml |
| 1000 mcg/ml |
Sample Problem:
A patient weighing 168 lbs. is ordered to receive Dobutamine (Dobutrex) at 8mcg/kg/min. The medication comes in 250mg to be diluted in 250 ml of D5W.
Compute for ml/hr: Answer should be rounded off to a whole number:
___________ ml/hr
STEP 1: Know the given.
Doctor’s order: 8mcg/kg/min
Client’s weight: 168 lb or 76.36
Available stock: 250 mg/250 ml
Convert 168 lb to kg.
Conversion factor: 1 kg = 2.2 lb
| 168 lb | | 1 kg |
|
| X |
|
| 1 | | 2.2 lb |
| 168 lb | | 1 kg |
|
| X |
|
| 1 | | 2.2 lb |
| 76.36 kg |
|
|
| 1 |
| 76.36 kg |
Step 2: Substitute the given to the formula.
| Doctor’s order (mcg/kg/min) | X | Client’s weight (kg) | X | 60 min/hr |
|
| ||||
| Stock dose (mcg/ml) | ||||
| Doctor’s order (8mcg/kg/min) | X | Client’s weight (76.36 kg) | X | 60 min/hr |
|
| ||||
| Stock dose (1000 mcg/ml) | ||||
| 8mcg/kg/min | X | 76.36 kg | X | 60 min/hr |
|
| ||||
| 1000 mcg/ml | ||||
| 8mcg/kg/min | X | 76.36 kg | X | 60 min/hr |
|
| | | ||
| 1000 mcg/ml | | | ||
| 36.6 ml/hr |
